Equirab Vaccine Overview Rabies is a deadly virus that targets mammals, including humans. Once symptoms appear, it’s almost always fatal, making vaccination crucial. Equirab has become one of the most trusted choices for rabies prevention, recommended by veterinarians and doctors worldwide. What is Equirab? Equirab is a rabies vaccine designed to provide strong and lasting protection. While primarily used for animals—especially horses—it is sometimes administered to human